“I Put a Spell on You” has been covered by other artists extensively. Although “Screamin'” Jay Hawkins' original 1956 version did not make any charts, several later cover versions have.

Nina Simone’s version reached No. 23 on the U.S. Billboard R&B chart in 1965; it also reached No. 49 on the UK singles chart that year, and No. 28 when it was reissued in 1969.